There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… Mehr…
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<
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There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… Mehr…
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<
Thalia.de
Nr. 24490291. Versandkosten:, Sofort per Download lieferbar, DE. (EUR 0.00) Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Tumor-Induced Immune Suppression ab 129.99 € als pdf eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin, Medien > Bücher, Tumor-Induced Immune Suppression
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(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… Mehr…
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<
Nr. 24490291. Versandkosten:, Sofort per Download lieferbar, DE. (EUR 0.00)
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… Mehr…
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<
Nr. 24490291. Versandkosten:, Sofort per Download lieferbar, DE. (EUR 0.00)
Tumor-Induced Immune Suppression ab 129.99 € als pdf eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin, Medien > Bücher, Tumor-Induced Immune Suppression
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Detailangaben zum Buch - Tumor-Induced Immune Suppression - Mechanisms and Therapeutic Reversal
EAN (ISBN-13): 9780387691183 ISBN (ISBN-10): 0387691189 Erscheinungsjahr: 2008 Herausgeber: Springer New York 301 Seiten Sprache: eng/Englisch
Buch in der Datenbank seit 2009-04-17T06:27:40+02:00 (Vienna) Detailseite zuletzt geändert am 2023-06-06T14:17:48+02:00 (Vienna) ISBN/EAN: 9780387691183
ISBN - alternative Schreibweisen: 0-387-69118-9, 978-0-387-69118-3 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: hurwitz Titel des Buches: tumor
Daten vom Verlag:
Autor/in: Dmitry I. Gabrilovich Titel: Tumor-Induced Immune Suppression - Mechanisms and Therapeutic Reversal Verlag: Springer; Springer US 302 Seiten Erscheinungsjahr: 2008-01-01 New York; NY; US Gedruckt / Hergestellt in Großbritannien. Sprache: Englisch 133,70 € (DE)
EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; Antigen; B7-H1/PD-1; Dendritic Cells; Immune Suppressive Mechanisms; Macrophages; T Cell; Tumor Development; apoptosis; cancer; immunobiology; inhibitory pathway; molecular mechanisms; regulation; B; Cancer Research; Immunology; Medical Microbiology; Cell Biology; Human Genetics; Developmental Biology; Cancer Biology; Immunology; Medical Microbiology; Cell Biology; Medical Genetics; Developmental Biology and Stem Cells; Biomedical and Life Sciences; Immunologie; Mikrobiologie und Virologie; Zellbiologie (Zytologie); Genetik, Medizin; Entwicklungsbiologie; BB
Tumor Induced Immune Suppression: Mechanisms and Therapeutic Reversal focuses on the critical question of tumor biology: "Why can tumors escape immune system control?" It also addresses one of the most important problems within the field of clinical oncology: the lack of efficient cancer vaccines. Edited by Dmitry Gabrilovich and Andy Hurwitz, the book is the first attempt at a systematic and comprehensive analysis of the various immunosuppressive mechanisms in cancer. This analysis includes information on: Different surface molecules that mediate T-cell suppression in cancer; The specific roles of dendritic cells, macrophages, and myeloid-derived suppressor cells in tumor non-responsiveness; The contribution of regulatory T cells in the inability of immune systems to mount antitumor response; The role of T-cell signaling and different metabolic pathways in tumor-associated immune suppression. This volume connects a multitude of different immunosuppressive mechanisms into one cohesive picture. Most of the chapters not only describe the biological phenomena, but also suggest specific approaches to their correction. This book should be of high interest for researchers in the fields of tumor immunology and general immunology, as well as for those who are involved in clinical oncology and cancer immunotherapy.
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