. .
Deutsch
Österreich
Ähnliche Bücher
Weitere, andere Bücher, die diesem Buch sehr ähnlich sein könnten:
Suchtools
Anmelden

Anmelden mit Facebook:

Registrieren
Passwort vergessen?


Such-Historie
Merkliste
Links zu eurobuch.at

Dieses Buch teilen auf…
..?
Buchtipps
Aktuelles
Tipp von eurobuch.at
Werbung
Bezahlte Anzeige
FILTER
- 0 Ergebnisse
Kleinster Preis: 79.00 EUR, größter Preis: 151.12 EUR, Mittelwert: 100.91 EUR
RNA interference Screens as a Tool for Discovering Gene Function - Siolas, Despina
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Siolas, Despina:

RNA interference Screens as a Tool for Discovering Gene Function - Taschenbuch

2010, ISBN: 3843375097, Lieferbar binnen 4-6 Wochen Versandkosten:Versandkostenfrei innerhalb der BRD

ID: 9783843375092

Internationaler Buchtitel. In englischer Sprache. Verlag: LAP Lambert Acad. Publ. Paperback, 208 Seiten, L=220mm, B=150mm, H=13mm, Gew.=326gr, [GR: 16780 - HC/Genetik/Gentechnologie], Kartoniert/Broschiert, Klappentext: Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies. Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies.

Neues Buch DEU
Buchgeier.com
Lieferbar binnen 4-6 Wochen (Besorgungstitel) Versandkosten:Versandkostenfrei innerhalb der BRD
Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Rna Interference Screens As A Tool For Discovering Gene Function - Despina Siolas
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)

Despina Siolas:

Rna Interference Screens As A Tool For Discovering Gene Function - neues Buch

ISBN: 9783843375092

Despina Siolas,Paperback, English-language edition,Pub by AV Akademikerverlag GmbH & Co. KG. Textbooks New Books ~~ Science~~ Life Sciences ~~ Genetics & Genomics RNA-interference-Screens-as-a-Tool-for-Discovering-Gene-Function~~Despina-Siolas AV Akademikerverlag GmbH & Co. KG. Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies.

Neues Buch [USA] Barnesandnoble.com
Free Shipping on eligible orders over $25 Versandkosten:zzgl. Versandkosten
Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
RNA Interference Screens as a Tool for Discovering Gene Function - Despina Siolas
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Despina Siolas:
RNA Interference Screens as a Tool for Discovering Gene Function - Taschenbuch

ISBN: 9783843375092

ID: 594518536

LAP LAMBERT Academic Publishing. Paperback. New. Paperback. 208 pages. Dimensions: 8.7in. x 5.9in. x 0.5in.Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200, 000 short hairpin RNA constructs targeting over 45, 000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cells genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN., LAP LAMBERT Academic Publishing

gebrauchtes bzw. antiquarisches Buch Biblio.com
BuySomeBooks
Versandkosten: EUR 9.77
Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
RNA interference Screens as a Tool for Discovering Gene Function - Siolas, Despina
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Siolas, Despina:
RNA interference Screens as a Tool for Discovering Gene Function - Taschenbuch

2010, ISBN: 3843375097

Gebundene Ausgabe, ID: 9816618

for cancer genetics studies - Buch, gebundene Ausgabe, 208 S., Beilagen: Paperback, Erschienen: 2010 LAP Lambert Acad. Publ.

Neues Buch Buch24.de
buch24de
Versandkosten:zzgl. Versandkosten
Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.

< zum Suchergebnis...
Details zum Buch
RNA interference Screens as a Tool for Discovering Gene Function
Autor:

Siolas, Despina

Titel:

RNA interference Screens as a Tool for Discovering Gene Function

ISBN-Nummer:

9783843375092

Recent advances in the field of RNA interference (RNAi) have enabled researchers to conduct in depth investigations of gene function using RNAi libraries. Our second-generation shRNA libraries consist of over 200,000 short hairpin RNA constructs targeting over 45,000 human and mouse genes modeled after primary miRNA transcripts. Each hairpin is linked to a unique 60 nucleotide identification sequence, which serves as a barcode and allows us to virtually count the number of cells that contain a specific hairpin in a cell population. Small changes in barcode copy number can be monitored through the use of microarray technology. The barcode can be amplified from a cell's genomic DNA and fluorescently labeled to produce a probe that is hybridized to a microarray. I applied this RNAi barcode screening method in a screen using a complex mixture of 7500 library hairpins in a p53 isogenic HCT 116 colon cancer cells to identify genes that modify sensitivity to a common chemotherapeutic, doxorubicin. This work illustrates the powerful use of RNAi screens to search for genes that synergize with existing therapeutics, and suggests strategies for genetically informed combination therapies.

Detailangaben zum Buch - RNA interference Screens as a Tool for Discovering Gene Function


EAN (ISBN-13): 9783843375092
ISBN (ISBN-10): 3843375097
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: LAP Lambert Acad. Publ.
208 Seiten
Gewicht: 0,326 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 14.11.2007 13:53:10
Buch zuletzt gefunden am 23.12.2014 11:52:25
ISBN/EAN: 9783843375092

ISBN - alternative Schreibweisen:
3-8433-7509-7, 978-3-8433-7509-2

< zum Suchergebnis...
< zum Archiv...
Benachbarte Bücher