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Transition Metal-Catalyzed Couplings in Process Chemistry - Javier Magano, Joshua R. Dunetz
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Javier Magano, Joshua R. Dunetz:
Transition Metal-Catalyzed Couplings in Process Chemistry - neues Buch

7, ISBN: 9783527658923

ID: 100659783527658923

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of a Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients. Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water. With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson's Process Solutions LLC. Technical & Industrial, Chemistry, Transition Metal-Catalyzed Couplings in Process Chemistry~~ Javier Magano, Joshua R. Dunetz~~Technical & Industrial~~Chemistry~~9783527658923, en, Transition Metal-Catalyzed Couplings in Process Chemistry, Javier Magano, Joshua R. Dunetz, 9783527658923, Wiley-VCH, 07/03/2013, , , , Wiley-VCH, 07/03/2013

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Transition Metal-Catalyzed Couplings in Process Chemistry - Wiley-VCH
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Transition Metal-Catalyzed Couplings in Process Chemistry - neues Buch

2013, ISBN: 9783527658923

ID: 572300917

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients. Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water. With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson´s Process Solutions LLC. Case Studies from the Pharmaceutical Industry eBook ePUB 02.07.2013 eBooks>Fremdsprachige eBooks>Englische eBooks>Sach- & Fachthemen>Medizin, Wiley-VCH, .201

Neues Buch Orellfuessli.ch
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Transition Metal-Catalyzed Couplings in Process Chemistry - Wiley-VCH
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Wiley-VCH:
Transition Metal-Catalyzed Couplings in Process Chemistry - neues Buch

2013, ISBN: 9783527658923

ID: 572300917

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in thisbook through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients.Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water.With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson´s Process Solutions LLC. Case Studies from the Pharmaceutical Industry eBook ePUB 02.07.2013 eBooks>Fremdsprachige eBooks>Englische eBooks>Sach- & Fachthemen>Medizin, Wiley-VCH, .201

Neues Buch Orellfuessli.ch
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Transition Metal-Catalyzed Couplings in Process Chemistry - Wiley-Vch
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Wiley-Vch:
Transition Metal-Catalyzed Couplings in Process Chemistry - neues Buch

2013, ISBN: 9783527658923

ID: 572300917

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in thisbook through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients.Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water.With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson´s Process Solutions LLC. Case Studies from the Pharmaceutical Industry eBook ePUB 02.07.2013 eBooks>Fremdsprachige eBooks>Englische eBooks>Sach- & Fachthemen>Medizin, Wiley-Vch, .201

Neues Buch Orellfuessli.ch
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Transition Metal-Catalyzed Couplings in Process Chemistry : Case Studies From the Pharmaceutical Industry - Kai Lai Chung
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2010, ISBN: 9783527658923

ID: 9783527658923

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients. Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water. With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson's Process Solutions LLC.; PDF; Scientific, Technical and Medical > Chemistry, Springer Berlin Heidelberg

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Detailangaben zum Buch - Transition Metal-Catalyzed Couplings in Process Chemistry - Case Studies from the Pharmaceutical Industry


EAN (ISBN-13): 9783527658923
ISBN (ISBN-10): 3527658920
Erscheinungsjahr: 2013
Herausgeber: Wiley-VCH
350 Seiten
Sprache: eng/Englisch

Buch in der Datenbank seit 12.11.2007 12:21:40
Buch zuletzt gefunden am 24.07.2018 16:04:44
ISBN/EAN: 9783527658923

ISBN - alternative Schreibweisen:
3-527-65892-0, 978-3-527-65892-3


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