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Qualitative and Quantitative Proteome Studies using Mass Spectrometry - A Study on the Mitochondrial Proteome - Hüber, Björn
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Hüber, Björn:

Qualitative and Quantitative Proteome Studies using Mass Spectrometry - A Study on the Mitochondrial Proteome - Taschenbuch

2010, ISBN: 9783639278385

[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphoryla… Mehr…

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Qualitative and Quantitative Proteome Studies using Mass Spectrometry - Björn Hüber
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Björn Hüber:

Qualitative and Quantitative Proteome Studies using Mass Spectrometry - Taschenbuch

ISBN: 9783639278385

[ED: Taschenbuch], [PU: VDM Verlag], Neuware - Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But sid… Mehr…

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Qualitative and Quantitative Proteome Studies using Mass Spectrometry
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Qualitative and Quantitative Proteome Studies using Mass Spectrometry - neues Buch

ISBN: 9783639278385

Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are… Mehr…

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Qualitative and Quantitative Proteome Studies using Mass Spectrometry - Taschenbuch

2010, ISBN: 9783639278385

Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are… Mehr…

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Qualitative and Quantitative Proteome Studies using Mass Spectrometry: A Study on the Mitochondrial Proteome - Hüber, Björn
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Hüber, Björn:
Qualitative and Quantitative Proteome Studies using Mass Spectrometry: A Study on the Mitochondrial Proteome - Taschenbuch

2010, ISBN: 9783639278385

VDM Verlag Dr. Müller, Taschenbuch, 96 Seiten, Publiziert: 2010-07-28T00:00:01Z, Produktgruppe: Book, 0.33 kg, Ingenieurwissenschaft & Technik, Naturwissenschaften & Technik, Kategorien, … Mehr…

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Qualitative and Quantitative Proteome Studies using Mass Spectrometry: A Study on the Mitochondrial Proteome

Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data.

Detailangaben zum Buch - Qualitative and Quantitative Proteome Studies using Mass Spectrometry: A Study on the Mitochondrial Proteome


EAN (ISBN-13): 9783639278385
ISBN (ISBN-10): 3639278380
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: VDM Verlag Dr. Müller
96 Seiten
Gewicht: 0,159 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 2009-08-26T20:25:20+02:00 (Vienna)
Detailseite zuletzt geändert am 2020-08-11T14:42:21+02:00 (Vienna)
ISBN/EAN: 9783639278385

ISBN - alternative Schreibweisen:
3-639-27838-0, 978-3-639-27838-5


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