[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 96, Selbstabholung und Barzahlung, PayPal, Offene Rechnung, Banküberweisung, Internationaler Versand
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[ED: Taschenbuch], [PU: VDM Verlag], Neuware - Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data., DE, [SC: 2.00], Neuware, gewerbliches Angebot, 221x152x12 mm, 96, [GW: 159g], PayPal, Offene Rechnung, Banküberweisung, Sofortüberweisung, Internationaler Versand
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Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Naturwissenschaften / Biologie, [PU: VDM Verlag Dr. Müller, Saarbrücken]
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Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data. Buch (fremdspr.) Björn Hüber Taschenbuch, VDM, 01.07.2010, VDM, 2010
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[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphoryla… Mehr…
[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 96, Selbstabholung und Barzahlung, PayPal, Offene Rechnung, Banküberweisung, Internationaler Versand<
Versandkosten:Versandkostenfrei, Versand nach Deutschland. (EUR 0.00) Syndikat Buchdienst
[ED: Taschenbuch], [PU: VDM Verlag], Neuware - Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But sid… Mehr…
[ED: Taschenbuch], [PU: VDM Verlag], Neuware - Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data., DE, [SC: 2.00], Neuware, gewerbliches Angebot, 221x152x12 mm, 96, [GW: 159g], PayPal, Offene Rechnung, Banküberweisung, Sofortüberweisung, Internationaler Versand<
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Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are… Mehr…
Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Naturwissenschaften / Biologie, [PU: VDM Verlag Dr. Müller, Saarbrücken]<
Nr. JAO8P4OCFD6. Versandkosten:, Lieferzeit: 5 Tage, DE. (EUR 0.00)
Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are… Mehr…
Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data. Buch (fremdspr.) Björn Hüber Taschenbuch, VDM, 01.07.2010, VDM, 2010<
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Mitochondria are often referred to as the cellular powerhouse due to their key function in the process of oxidative phosphorylation. But side reactions of the electron transport chain are implemented in the generation of reactive oxygen species. These ROS are highly reactive and cause damage to biological molecules. The free radical theory of ageing hypothesizes that such damage is the primary mechanism of ageing. Therefore the search for proteins that are targets of damage is of critical importance to understand the role of oxidative stress in ageing. Proteomics combined with MS provides a powerful suite of techniques for the identification of these proteins. We focused on the development and refinement of a proteomic workflow aiming to produce a high quality quantitative survey of the mitochondrial proteome. We performed qualitative LC-MS/MS-based experiments on mitochondria proteins by means of both gel-based and gel-free approaches, showing an over 4-fold increase in protein identifications by the latter. In addition first quantitative results were collected, yielding in the quantitation of 599 proteins, illustrating the potential of the developed method and the acquired data.
Detailangaben zum Buch - Qualitative and Quantitative Proteome Studies using Mass Spectrometry: A Study on the Mitochondrial Proteome
EAN (ISBN-13): 9783639278385 ISBN (ISBN-10): 3639278380 Gebundene Ausgabe Taschenbuch Erscheinungsjahr: 2010 Herausgeber: VDM Verlag Dr. Müller 96 Seiten Gewicht: 0,159 kg Sprache: eng/Englisch
Buch in der Datenbank seit 2009-08-26T20:25:20+02:00 (Vienna) Detailseite zuletzt geändert am 2020-08-11T14:42:21+02:00 (Vienna) ISBN/EAN: 9783639278385
ISBN - alternative Schreibweisen: 3-639-27838-0, 978-3-639-27838-5