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Biology of Immune Regulation in Multiple Myeloma: Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma - Karthick Raja Muthu Raja, Roman Hajek
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Karthick Raja Muthu Raja, Roman Hajek:
Biology of Immune Regulation in Multiple Myeloma: Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma - Taschenbuch

2013, ISBN: 3659369144

[SR: 8165714], Paperback, [EAN: 9783659369148], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2013-03-20, LAP LAMBERT Academic Publishing, Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (≤ 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune respon, 173514, Medical Books, 227560, Administration & Medicine Economics, 227571, Allied Health Professions, 227191, Basic Sciences, 227604, Dentistry, 3559244011, History, 266181, Medical Informatics, 265542, Medicine, 227640, Nursing, 265544, Pharmacology, 6511980011, Psychology, 227677, Research, 227719, Veterinary Medicine, 1000, Subjects, 283155, Books

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Biology of Immune Regulation in Multiple Myeloma: Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma - Karthick Raja Muthu Raja, Roman Hajek
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Karthick Raja Muthu Raja, Roman Hajek:
Biology of Immune Regulation in Multiple Myeloma: Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma - Taschenbuch

2013, ISBN: 3659369144

[SR: 8165714], Paperback, [EAN: 9783659369148], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2013-03-20, LAP LAMBERT Academic Publishing, Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (≤ 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune respon, 173514, Medical Books, 227560, Administration & Medicine Economics, 227571, Allied Health Professions, 227191, Basic Sciences, 227604, Dentistry, 3559244011, History, 266181, Medical Informatics, 265542, Medicine, 227640, Nursing, 265544, Pharmacology, 6511980011, Psychology, 227677, Research, 227719, Veterinary Medicine, 1000, Subjects, 283155, Books

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Biology of Immune Regulation in Multiple Myeloma - Roman Hajek#Karthick Raja Muthu Raja
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Roman Hajek#Karthick Raja Muthu Raja:
Biology of Immune Regulation in Multiple Myeloma - neues Buch

2013, ISBN: 9783659369148

ID: 580571674

Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (= 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune responses. Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma Bücher > Fremdsprachige Bücher > Englische Bücher Taschenbuch 21.03.2013 Buch (dtsch.), LAP Lambert Academic Publishing, .201

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Biology of Immune Regulation in Multiple Myeloma - Roman Hajek#Karthick Raja Muthu Raja
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Roman Hajek#Karthick Raja Muthu Raja:
Biology of Immune Regulation in Multiple Myeloma - neues Buch

2013, ISBN: 9783659369148

ID: 796331215

Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (= 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune responses. Evaluation of immune regulatory cells and their clinical significance in patients with multiple myeloma Buch (dtsch.) Taschenbuch 21.03.2013 Bücher>Fremdsprachige Bücher>Englische Bücher, LAP Lambert Academic Publishing, .201

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Biology of Immune Regulation in Multiple Myeloma - Muthu Raja, Karthick Raja Hajek, Roman
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Muthu Raja, Karthick Raja Hajek, Roman:
Biology of Immune Regulation in Multiple Myeloma - Taschenbuch

ISBN: 9783659369148

[ED: Softcover], [PU: LAP Lambert Academic Publishing], Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (= 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune responses. Versandfertig in 3-5 Tagen, Neuware, gewerbliches Angebot

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Biology of Immune Regulation in Multiple Myeloma

Multiple myeloma (MM) is a malignancy of plasma cells (PCs) which accumulate in the bone marrow (BM), thus, leading to anemia, bone lesions, hypercalcemia, renal impairment and immune dysfunction. T regulatory (Treg) cells maintain immune homeostasis in healthy individuals by patrolling unwanted immune responses. Whereas in cancer patients, these cells are uncontrollably expanded, thereby, inhibiting the host anti-tumor responses. Majorly this work is focused to understand the role of Treg cells, including CD4 Treg cells and CD8 Treg cells in rendering the immune impairments in MM patients. This study clearly showed that both CD4 and CD8 Treg cells were functionally suppressive and increased in MM patients. These findings were confirmed by using different methods, including flow cytometry, functional and molecular studies (RT-PCR and western blot). Clinical significance of this study was CD4 Treg cells were found to be increased in patients with shorter time to progression, hypercalcemia, lower normal PC counts (≤ 5%) and IgA myeloma subtype. From these findings, Treg cells could be considered as one of the evasion mechanisms of myeloma cells from host immune respon

Detailangaben zum Buch - Biology of Immune Regulation in Multiple Myeloma


EAN (ISBN-13): 9783659369148
ISBN (ISBN-10): 3659369144
Taschenbuch
Erscheinungsjahr: 2013
Herausgeber: LAP LAMBERT Academic Publishing

Buch in der Datenbank seit 10.10.2014 09:34:22
Buch zuletzt gefunden am 05.01.2018 13:09:42
ISBN/EAN: 9783659369148

ISBN - alternative Schreibweisen:
3-659-36914-4, 978-3-659-36914-8


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