2013, ISBN: 3642267017

[EAN: 9783642267017], Neubuch, [SC: 0.0], [PU: Springer Berlin Heidelberg], INDOLEDERIVATIVES; ISOQUINOLINEDERIVATIVES; MULTI-COMPONENTREACTION; MULTICOMPONENTCOUPLING; ONE-POTREACTION; A… Mehr…

[EAN: 9783642267017], Neubuch, [SC: 0.0], [PU: Springer Berlin Heidelberg], INDOLEDERIVATIVES; ISOQUINOLINEDERIVATIVES; MULTI-COMPONENTREACTION; MULTICOMPONENTCOUPLING; ONE-POTREACTION; ATOMECONOMY; BIOACTIVECOMPOUNDS; COMPLEXHETEROCYCLICSTRUCTURES; COPPERSALT; GREENCHEMISTRY, Druck auf Anfrage Neuware - Printed after ordering - A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, extensive application studies using one-pot palladium-, acid-, or base-promoted cyclization revealed that indole- or isoquinoline-fused polycyclic compounds can be readily synthesized through multi-component reactions. As the concept of Green Chemistry becomes ever more important, these findings may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. This could lead to development of promising drug leads with structural complexity. The work of this thesis will go on to inspire the synthetic research of many readers., Books<

2013, ISBN: 3642267017

[EAN: 9783642267017], Neubuch, [PU: Springer Berlin Heidelberg], ATOMECONOMY; BIOACTIVECOMPOUNDS; COMPLEXHETEROCYCLICSTRUCTURES; COPPERSALT; GREENCHEMISTRY; INDOLEDERIVATIVES; ISOQUINOLIN… Mehr…

[EAN: 9783642267017], Neubuch, [PU: Springer Berlin Heidelberg], ATOMECONOMY; BIOACTIVECOMPOUNDS; COMPLEXHETEROCYCLICSTRUCTURES; COPPERSALT; GREENCHEMISTRY; INDOLEDERIVATIVES; ISOQUINOLINEDERIVATIVES; MULTI-COMPONENTREACTION; MULTICOMPONENTCOUPLING; ONE-POTREACTION, Druck auf Anfrage Neuware -A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, extensive application studies using one-pot palladium-, acid-, or base-promoted cyclization revealed that indole- or isoquinoline-fused polycyclic compounds can be readily synthesized through multi-component reactions. As the concept of Green Chemistry becomes ever more important, these findings may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. This could lead to development of promising drug leads with structural complexity. The work of this thesis will go on to inspire the synthetic research of many readers. 120 pp. Englisch, Books<

2013, ISBN: 3642267017

2011 Kartoniert / Broschiert Organische Chemie, atomeconomy; Bioactivecompounds; complexheterocyclicstructures; coppersalt; greenchemistry; indolederivatives; isoquinolinederivatives; m… Mehr…

2011 Kartoniert / Broschiert Organische Chemie, atomeconomy; Bioactivecompounds; complexheterocyclicstructures; coppersalt; greenchemistry; indolederivatives; isoquinolinederivatives; multi-componentreaction; multicomponentcoupling; one-potreaction, mit Schutzumschlag 11, [PU:Springer Berlin Heidelberg; Springer Berlin]<

2013, ISBN: 9783642267017

Synthesis of Nitrogen-Containing Polycyclic Compounds, Buch, Softcover, 2011, [PU: Springer Berlin], Springer Berlin, 2013

ISBN: 9783642267017

paperback, [PU: Springer, Berlin/Heidelberg/New York, NY]